Metabolic fate of 2,4-dichlorophenol and related plant residues in rats.

@article{PascalLorber2012MetabolicFO,
  title={Metabolic fate of 2,4-dichlorophenol and related plant residues in rats.},
  author={Sophie Pascal-Lorber and Sabrina Despoux and Emilien L. Jamin and C{\'e}cile Canlet and J. -P. Cravedi and François Laurent},
  journal={Journal of agricultural and food chemistry},
  year={2012},
  volume={60 7},
  pages={1728-36}
}
This study compared the metabolic fate of [(14)C]-DCP, [(14)C]-residues from radish plants, and purified [(14)C]-DCP-(acetyl)glucose following oral administration in rats. A rapid excretion of radioactivity in urine occurred for [(14)C]-DCP, [(14)C]-DCP-(acetyl)glucose, and soluble residues, 69, 85, and 69% within 48 h, respectively. Radio-HPLC profiles of 0-24 h urine from rats fed [(14)C]-DCP and [(14)C]-DCP-(acetyl)glucose were close and qualitatively similar to those obtained from plant… CONTINUE READING

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