Metabolic engineering.

  title={Metabolic engineering.},
  author={G. Stephanopoulos},
  journal={Biotechnology and bioengineering},
  volume={58 2-3},
  • G. Stephanopoulos
  • Published 1998
  • Medicine
  • Biotechnology and bioengineering
  • Metabolic engineering is the science that combines systematic analysis of metabolic and other pathways with molecular biological techniques to improve cellular properties by designing and implementing rational genetic modifications. As such, metabolic engineering deals with the measurement of metabolic fluxes and elucidation of their control as determinants of metabolic function and cell physiology. A novel aspect of metabolic engineering is that it departs from the traditional reductionist… CONTINUE READING

    Topics from this paper.

    Progress in Metabolic Engineering of Saccharomyces cerevisiae
    • 510
    • PDF
    How will bioinformatics influence metabolic engineering?
    • 96
    • PDF
    Metabolic engineering of Escherichia coli for the efficient utilization of plant sugar mixture
    Nonstationary metabolic flux analysis (NMFA) for the elucidation of cellular physiology
    Functional similarities of reaction sets in metabolic pathways
    • 7
    • PDF


    Publications referenced by this paper.
    Metabolic fluxes and metabolic engineering.
    • 539
    Toward a science of metabolic engineering
    • 1,031
    Network rigidity and metabolic engineering in metabolite overproduction
    • 537
    Metabolic Engineering of Propanediol Pathways
    • 196
    Flux amplification in complex metabolic networks
    • 89
    Combinatorial biosynthesis for new drug discovery.
    • 108
    Metabolic fluxes in riboflavin-producing Bacillus subtilis
    • 248
    Stoichiometric interpretation of Escherichia coli glucose catabolism under various oxygenation rates.
    • 301
    • PDF