Metabolic engineering of the moss Physcomitrella patens to produce the sesquiterpenoids patchoulol and α/β-santalene

@inproceedings{Zhan2014MetabolicEO,
  title={Metabolic engineering of the moss Physcomitrella patens to produce the sesquiterpenoids patchoulol and α/β-santalene},
  author={Xin Zhan and Yu-Hua Zhang and Dong-Fang Chen and Henrik Toft Simonsen},
  booktitle={Front. Plant Sci.},
  year={2014}
}
The moss Physcomitrella patens, has been genetically engineered to produce patchoulol and β-santalene, two valuable sesquiterpenoid ingredients in the fragrance industry. The highest yield of patchoulol achieved was 1.34 mg/g dry weight. This was achieved by non-targeted transformation of the patchoulol synthase and either a yeast or P. patens HMGR gene under the control of a 35S promoter. Santalene synthase targeted to the plastids yielded 0.039 mg/g dry weight of α/β santalene; cytosolic… CONTINUE READING
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Citation: Zhan X, Zhang Y-H, Chen D-F and Simonsen HT (2014) Metabolic engineering of the moss Physcomitrella patens to produce the sesquiterpenoids patchoulol and α/β-santalene

November
Front. Plant Sci. 5:636. doi: 10.3389/fpls.2014.00636 This article was submitted to Plant Biotechnology, a section of the journal Frontiers in • 2014
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