Metabolic engineering of Escherichia coli for production of valerenadiene.

Abstract

Valeriana officinalis is a medicinal herb which produces a suite of compounds in its root tissue useful for treatment of anxiety and insomnia. The sesquiterpene components of the root extract, valerenic acid and valerena-1,10-diene, are thought to contribute to most of the observed anxiolytic of Valerian root preparations. However, valerenic acid and its… (More)
DOI: 10.1016/j.jbiotec.2017.10.004

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