Metabolic engineering of Enterobacter cloacae for high-yield production of enantiopure (2R,3R)-2,3-butanediol from lignocellulose-derived sugars.

@article{Li2015MetabolicEO,
  title={Metabolic engineering of Enterobacter cloacae for high-yield production of enantiopure (2R,3R)-2,3-butanediol from lignocellulose-derived sugars.},
  author={Lixiang Li and Kun Li and Yu Wang and Chao Chen and Youqiang Xu and Lijie Zhang and Binbin Han and Chengyong Gao and Fei Tao and Cuiqing Ma and Ping Xu},
  journal={Metabolic engineering},
  year={2015},
  volume={28},
  pages={19-27}
}
Biotechnological production of biofuels is restricted by toxicity of the products such as ethanol and butanol. As its low toxicity to microbes, 2,3-butanediol (2,3-BD), a fuel and platform bio-chemical, could be a promising alternative for biofuel production from renewable bioresources. In addition, no bacterial strains have been reported to produce enantiopure 2,3-BD using lignocellulosic hydrolysates. In this study, Enterobacter cloacae strain SDM was systematically and metabolically… CONTINUE READING
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