Metabolic encephalopathy as a complication of renal failure: mechanisms and mediators.

@article{Fraser1994MetabolicEA,
  title={Metabolic encephalopathy as a complication of renal failure: mechanisms and mediators.},
  author={Cosmo L Fraser and Allen Israel Arieff},
  journal={New horizons},
  year={1994},
  volume={2 4},
  pages={518-26}
}
Among patients with end-stage renal disease, nervous system dysfunction remains a major cause of disability. Patients with chronic renal failure who have not yet received dialysis may develop symptoms ranging from mild sensorial clouding to delirium and coma. Dialysis itself is associated with at least three distinct disorders of the CNS: dialysis disequilibrium syndrome; dialysis dementia; and progressive intellectual dysfunction. Peripheral neuropathy is also a major cause of disability in… CONTINUE READING