Metabolic effects of new oral hypoglycemic agent CS-045 in NIDDM subjects.
@article{Suter1992MetabolicEO,
title={Metabolic effects of new oral hypoglycemic agent CS-045 in NIDDM subjects.},
author={Stephan L. Suter and John J. Nolan and Penny Wallace and Barry Gumbiner and Jerrold M. Olefsky},
journal={Diabetes care},
year={1992},
volume={15 2},
pages={
193-203
}
}
OBJECTIVE
To study the metabolic effects of a new oral antidiabetic agent, CS-045, in subjects with non-insulin-dependent diabetes mellitus (NIDDM).
RESEARCH DESIGN AND METHODS
Eleven NIDDM subjects (mean age 59 yr and body mass index 32.3) were treated with 400 mg/day CS-045 for 6-12 wk. Patients were hospitalized before and at the end of the drug-treatment period for metabolic studies, including oral glucose tolerance test (OGTT), meal tolerance test (MTT), euglycemic glucose-clamp studies… CONTINUE READING