Metabolic effects of i.v. propacetamol, metamizol or external cooling in critically ill febrile sedated patients.

@article{Poblete1997MetabolicEO,
  title={Metabolic effects of i.v. propacetamol, metamizol or external cooling in critically ill febrile sedated patients.},
  author={Beate Poblete and Jacques Andr{\'e} Romand and Claude Pichard and Paul A Koenig and Peter M. Suter},
  journal={British journal of anaesthesia},
  year={1997},
  volume={78 2},
  pages={123-7}
}
We have measured the metabolic response to sequential administration of propacetamol, metamizol and/or external cooling in 20 febrile patients under sedation and analgesia and during mechanical ventilation. There was no change in temperature (T degree) after propacetamol therapy, whereas after metamizol only a small decrease was noted (from 38.9 (SEM 0.2) to 38.5 (0.3) degrees C; P = 0.02). External cooling produced a significant decrease in T degree (39.1 (0.2) to 37.1 (0.2) degrees C; P < 0… CONTINUE READING
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