Metabolic effects of citrate- vs bicarbonate-based substitution fluid in continuous venovenous hemofiltration: a prospective sequential cohort study.

@article{Aman2010MetabolicEO,
  title={Metabolic effects of citrate- vs bicarbonate-based substitution fluid in continuous venovenous hemofiltration: a prospective sequential cohort study.},
  author={Jurjan Aman and Shaikh A. Nurmohamed and Marc G Vervloet and A. B. Johan Groeneveld},
  journal={Journal of critical care},
  year={2010},
  volume={25 1},
  pages={120-7}
}
BACKGROUND Studies investigating the metabolic effects of citrate-based substitution fluids are lacking. This study aims to compare the effect of citrate- vs bicarbonate-based substitution fluid used during continuous venovenous hemofiltration (CVVH) for acute kidney injury on acid-base balance and electrolytes in critically ill patients. METHODS This was a prospective sequential cohort study in patients with a contraindication for systemic anticoagulation. The first cohort was treated by… CONTINUE READING