Metabolic cross-feeding via intercellular nanotubes among bacteria.

  title={Metabolic cross-feeding via intercellular nanotubes among bacteria.},
  author={Samay Pande and Shraddha Shitut and Lisa Patricia Freund and Martin Westermann and Felix Bertels and Claudia Colesie and Ilka B. Bischofs and Christian Kost},
  journal={Nature communications},
Bacteria frequently exchange metabolites by diffusion through the extracellular environment, yet it remains generally unclear whether bacteria can also use cell-cell connections to directly exchange nutrients. Here we address this question by engineering cross-feeding interactions within and between Acinetobacter baylyi and Escherichia coli, in which two distant bacterial species reciprocally exchange essential amino acids. We establish that in a well-mixed environment E. coli, but likely not A… CONTINUE READING
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