Metabolic costs and evolutionary implications of human brain development

@article{Kuzawa2014MetabolicCA,
  title={Metabolic costs and evolutionary implications of human brain development},
  author={Christopher W. Kuzawa and Harry T. Chugani and Lawrence I. Grossman and Leonard Lipovich and Otto Muzik and Patrick R. Hof and Derek E. Wildman and Chet C. Sherwood and William R. Leonard and Nicholas T. Lange},
  journal={Proceedings of the National Academy of Sciences},
  year={2014},
  volume={111},
  pages={13010 - 13015}
}
Significance The metabolic costs of brain development are thought to explain the evolution of humans’ exceptionally slow and protracted childhood growth; however, the costs of the human brain during development are unknown. We used existing PET and MRI data to calculate brain glucose use from birth to adulthood. We find that the brain’s metabolic requirements peak in childhood, when it uses glucose at a rate equivalent to 66% of the body’s resting metabolism and 43% of the body’s daily energy… 

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