Metabolic control via the mitochondrial protein import machinery.

Abstract

Mitochondria have to import most of their proteins in order to fulfill a multitude of metabolic functions. Sophisticated import machineries mediate targeting and translocation of preproteins from the cytosol and subsequent sorting into their suborganellar destination. The mode of action of these machineries has been considered for long time as a static and… (More)
DOI: 10.1016/j.ceb.2014.11.001

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