Metabolic control of puberty onset: new players, new mechanisms.


Puberty, as the end-point of a complex series of maturational events affecting the components of the hypothalamic-pituitary-gonadal (HPG) axis, is gated by the state of body energy reserves and sensitive to different metabolic cues; conditions of severe metabolic stress and energy unbalance (from anorexia to morbid obesity) being commonly linked to… (More)
DOI: 10.1016/j.mce.2009.12.018


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