Metabolic click-labeling with a fucose analog reveals pectin delivery, architecture, and dynamics in Arabidopsis cell walls.

@article{Anderson2012MetabolicCW,
  title={Metabolic click-labeling with a fucose analog reveals pectin delivery, architecture, and dynamics in Arabidopsis cell walls.},
  author={Charles T Anderson and Ian S Wallace and Chris R Somerville},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2012},
  volume={109 4},
  pages={1329-34}
}
Polysaccharide-rich cell walls are a defining feature of plants that influence cell division and growth, but many details of cell-wall organization and dynamics are unknown because of a lack of suitable chemical probes. Metabolic labeling using sugar analogs compatible with click chemistry has the potential to provide new insights into cell-wall structure and dynamics. Using this approach, we found that an alkynylated fucose analog (FucAl) is metabolically incorporated into the cell walls of… CONTINUE READING
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