Metabolic changes in early poststatus epilepticus measured by MR spectroscopy in rats

  title={Metabolic changes in early poststatus epilepticus measured by MR spectroscopy in rats},
  author={Yijen L. Wu and Patrice S. Pearce and Amedeo Rapuano and T. Kevin Hitchens and Nihal C. de Lanerolle and Jullie W Pan},
  journal={Journal of Cerebral Blood Flow \& Metabolism},
  pages={1862 - 1870}
There is little experimental in vivo data on how differences in seizure duration in experimental status epilepticus influence metabolic injury. This is of interest given that in humans, status duration is a factor that influences the probability of subsequent development of epilepsy. This question is studied using 7-T magnetic resonance (MR) spectroscopy, T2 relaxometry in the incremented kainate rodent model of temporal lobe epilepsy, using two durations of status epilepticus, 1.5 and 3 hours… 
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