Metabolic capacity of nasal tissue interspecies comparisons of xenobiotic-metabolizing enzymes.

@article{ThorntonManning1997MetabolicCO,
  title={Metabolic capacity of nasal tissue interspecies comparisons of xenobiotic-metabolizing enzymes.},
  author={Janice R. Thornton-Manning and Ashley R. Dahl},
  journal={Mutation research},
  year={1997},
  volume={380 1-2},
  pages={43-59}
}
High levels of xenobiotic-metabolizing enzymes occur in the nasal mucosa of all species studied. In certain species, including rats and rabbits, unique enzymes are present in the nasal mucosa. The function of these enzymes is not well understood, but it is thought that they play a role in protecting the lungs from toxicity of inhalants. The observation that several nasal xenobiotic-metabolizing enzymes accept odorants as substrates may indicate that these enzymes also play a role in the… CONTINUE READING

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