Metabolic and proteomic differentials in head and neck squamous cell carcinomas and normal gingival tissue

@article{Ziebart2010MetabolicAP,
  title={Metabolic and proteomic differentials in head and neck squamous cell carcinomas and normal gingival tissue},
  author={Thomas Ziebart and Stefan Walenta and Martin Kunkel and Torsten Eugen Reichert and Wilfried Wagner and Wolfgang F Mueller-Klieser},
  journal={Journal of Cancer Research and Clinical Oncology},
  year={2010},
  volume={137},
  pages={193-199}
}
A high lactate content in malignant head and neck cancer (Head and neck squamous cell carcinomas, HNSCC) is associated with a higher risk of metastatic spread and lower overall patient survival. However, until present, the underlying mechanisms are not clearly understood. Here, a systematic comparison of glucose metabolism in HNSCC and homologous normal tissue is presented for the first time. The concentrations of glucose, lactate and ATP were measured in cryobiopsies of 29 human HNSCC and of 9… CONTINUE READING

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DeWnitionen zum radikalchirurgischen Vorgehen bei Plattenepithelkarzinomen der Mundhöhle

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Highly Influential
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