Metabolic and mitochondrial dysfunction in early mouse embryos following maternal dietary protein intervention.

@article{Mitchell2009MetabolicAM,
  title={Metabolic and mitochondrial dysfunction in early mouse embryos following maternal dietary protein intervention.},
  author={Megan S Mitchell and Samantha L Schulz and David T Armstrong and Michelle Lane},
  journal={Biology of reproduction},
  year={2009},
  volume={80 4},
  pages={622-30}
}
Dietary supply of nutrients, both periconception and during pregnancy, influence the growth and development of the fetus and offspring and their health into adult life. Despite the importance of research efforts surrounding the developmental origins of health and disease hypothesis, the biological mechanisms involved remain elusive. Mitochondria are of major importance in the oocyte and early embryo, particularly as a source of ATP generation, and perturbations in their function have been… CONTINUE READING

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