Metabolic and cardiovascular effects of carvedilol and atenolol in non-insulin-dependent diabetes mellitus and hypertension. A randomized, controlled trial.

@article{Giugliano1997MetabolicAC,
  title={Metabolic and cardiovascular effects of carvedilol and atenolol in non-insulin-dependent diabetes mellitus and hypertension. A randomized, controlled trial.},
  author={Dario Giugliano and Rosa Acampora and Raffaele Marfella and Nicla de Rosa and Patrizia Ziccardi and R. Ragone and Lorenita De Angelis and F D'onofrio},
  journal={Annals of internal medicine},
  year={1997},
  volume={126 12},
  pages={955-9}
}
BACKGROUND Diabetic patients are considered less suitable than nondiabetic patients for beta-blocker therapy because of the risk for worsened glucose and lipid metabolism and more severe hypoglycemic attacks. OBJECTIVE To compare the metabolic and cardiovascular effects of carvedilol with those of atenolol in diabetic patients with hypertension. DESIGN Randomized, double-blind, 24-week trial. SETTING University hospital clinic. PATIENTS 45 patients with non-insulin-dependent diabetes… CONTINUE READING

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