Metabolic and anthropometric evaluation of insulin resistance in nondiabetic patients with nonalcoholic steatohepatitis

@article{Chalasani2003MetabolicAA,
  title={Metabolic and anthropometric evaluation of insulin resistance in nondiabetic patients with nonalcoholic steatohepatitis},
  author={Naga Chalasani and Mark A. Deeg and Scott A. Persohn and David W Crabb},
  journal={American Journal of Gastroenterology},
  year={2003},
  volume={98},
  pages={1849-1855}
}
OBJECTIVES:Insulin resistance is nearly universal in patients with nonalcoholic steatohepatitis (NASH) when tested by glucose tolerance tests or clamp methods. However, the pattern of insulin resistance in these patients after a physiological challenge is unknown. We conducted a study to characterize the metabolic response to a mixed meal in nondiabetic patients with NASH (NDN) and to identify anthropometric determinants of insulin resistance in these patients.METHODS:Serum insulin, C-peptide… CONTINUE READING