Metabolic and Functional Studies on Activated Mouse Macrophages

  title={Metabolic and Functional Studies on Activated Mouse Macrophages},
  author={Marion Stubbs and Alice Vreeland K{\"u}hner and Elvera A. Glass and John R. David and Manfred L. Karnovsky},
  journal={The Journal of Experimental Medicine},
  pages={537 - 542}
The macrophage responds to some infections with an adaptive increase in its defense capacities. Mackaness (1) has shown that the enhancement of macrophage function during infection has an immunologic basis and involves the lymphocyte. The "ac t iva ted" macrophages obtained from animals during a certain stage of infection spread out on glass more extensively, appear more heavily endowed with mitochondria and lysosomes, are more phagocytic, and are better able to kill bacteria than their normal… CONTINUE READING

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Infectious Agents and Host Reactions

  • G. B. Mackaness
  • 1970

Studies on the interaction between phagocytes and tubercle bacilli

  • Stihelin, ill, M. L. Karnovsky, E. Suter
  • Y. Exp. Med
  • 1956

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