Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescence.

Werner Zwerschke, Sybille Mazurek, Petra Stöckl, Eveline Huetter, Erich Eigenbrodt, Pidder Jansen-Duerr
Published 2003 in The Biochemical journal

Abstract

Cellular senescence is considered a major tumour-suppressor mechanism in mammals, and many oncogenic insults, such as the activation of the ras proto-oncogene, trigger initiation of the senescence programme. Although it was shown that activation of the senescence programme involves the up-regulation of cell-cycle regulators such as the inhibitors of cyclin… (More)

Mitochondrial (Dys) Function in Inflammaging: Do MitomiRs Influence the Energetic, Oxidative, and Inflammatory Status of Senescent Cells?

Angelica Giuliani, Francesco Prattichizzo, Luigina Micolucci, Antonio Ceriello, Antonio Domenico Procopio, Maria Rita Rippo
Mediators of inflammation
2017

Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescence.

Abstract

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Mitochondrial (Dys) Function in Inflammaging: Do MitomiRs Influence the Energetic, Oxidative, and Inflammatory Status of Senescent Cells?

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References

Slides referencing similar topics

Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescence.

Abstract

Topics

Figures and Tables

Cited By

Mitochondrial (Dys) Function in Inflammaging: Do MitomiRs Influence the Energetic, Oxidative, and Inflammatory Status of Senescent Cells?

Prognostic significance of synergistic hexokinase-2 and beta2-adrenergic receptor expression in human hepatocelluar carcinoma after curative resection

Mitochondrial effectors of cellular senescence: beyond the free radical theory of aging

Are there roles for brain cell senescence in aging and neurodegenerative disorders?

Cytosolic malate dehydrogenase regulates senescence in human fibroblasts

Mitochondria: Are they causal players in cellular senescence?

Mitochondrial ageing in rat brain areas and human fibroblasts

A mitochondrial view of aging, reactive oxygen species and metastatic cancer.

Analysis of Gene Expression in Human Dermal Fibroblasts Treated with Senescence-Modulating COX Inhibitors

Caveolin‐1 deficiency induces premature senescence with mitochondrial dysfunction

References

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