Metabolic alterations in the prefrontal and cingulate cortices are related to behavioral deficits in a rodent model of attention-deficit hyperactivity disorder.

@article{Barbelivien2001MetabolicAI,
  title={Metabolic alterations in the prefrontal and cingulate cortices are related to behavioral deficits in a rodent model of attention-deficit hyperactivity disorder.},
  author={Alexandra Barbelivien and Sirja Ruotsalainen and Jouni Sirvi{\"o}},
  journal={Cerebral cortex},
  year={2001},
  volume={11 11},
  pages={1056-63}
}
Rats with a deficit in selective attention accompanied by impulsivity can be identified using a five-choice serial reaction time task (5-CSRT) and have been proposed to represent a rodent model of attention-deficit hyperactivity disorder (ADHD). The aim of the present study was to investigate which brain areas are important for visuospatial attention and to test the specific hypothesis that dysfunction of the frontal cortex is related to the behavioral deficits observed in poorly performing… CONTINUE READING

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