Metabolic alterations and systemic inflammation in obstructive sleep apnea among nonobese and obese prepubertal children.

@article{Gozal2008MetabolicAA,
  title={Metabolic alterations and systemic inflammation in obstructive sleep apnea among nonobese and obese prepubertal children.},
  author={David Gozal and Oscar Sans Capdevila and Leila Kheirandish-Gozal},
  journal={American journal of respiratory and critical care medicine},
  year={2008},
  volume={177 10},
  pages={1142-9}
}
RATIONALE Obstructive sleep apnea (OSA) has been associated with a higher prevalence and severity of the metabolic syndrome in adult patients, even after controlling for obesity. In contrast, OSA in prepubertal children does not appear to correlate with the magnitude of such metabolic derangements. OBJECTIVES To further establish the potential mechanistic role of OSA in metabolic regulation in prepubertal children. METHODS Fasting glucose, insulin, C-reactive protein, apolipoprotein B, and… CONTINUE READING