Corpus ID: 24055081

Metabolic activity in the areas of new fill-in after thallium-201 reinjection: comparison with positron emission tomography using fluorine-18-deoxyglucose.

  title={Metabolic activity in the areas of new fill-in after thallium-201 reinjection: comparison with positron emission tomography using fluorine-18-deoxyglucose.},
  author={N. Tamaki and H. Ohtani and K. Yamashita and Y. Magata and Y. Yonekura and R. Nohara and H. Kambara and C. Kawai and K. Hirata and T. Ban},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  volume={32 4},
  • N. Tamaki, H. Ohtani, +7 authors T. Ban
  • Published 1991
  • Chemistry, Medicine
  • Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Reinjection of thallium-201 after recording the 3-hr delayed scan often demonstrates improvement in areas of persistent abnormalities. To determine the metabolic activity of these areas, the changes seen on stress/redistribution/reinjection thallium SPECT were compared with PET using fluorine-18-fluorodeoxyglucose (FDG) in 18 patients with coronary artery disease. Of 48 segments showing no redistribution on the delayed scan, the reinjection scan identified new fill-in in 20 segments (42%), all… Expand
Thallium-201 single photon emission tomography of myocardium: Additional information in reinjection studies is dependent on collateral circulation
A second thallium-201 injection under resting conditions is able to improve the differentiation between myocardial scar and ischaemia when compared with simple redistribution imaging, and the dependence on the degree of stenosis and the presence of collaterals was evaluated. Expand
Impaired fatty acid uptake in ischemic but viable myocardium identified by thallium-201 reinjection.
Reduction in BMIPP activity compared with differential uptake of thallium, an index of resting myocardial perfusion, is consistent with impaired fatty acid uptake in ischemic myocardium, particularly in the area of fill-in afterThallium reinjection. Expand
Thallium-201 reinjection images can identify the viable and necrotic myocardium similarly to metabolic imaging with glucose loading18F-fluorodeoxyglucose (18FDG)-PET
Reinjection imaging identified the viable and necrotic myocardium similarly to metabolic imaging obtained by18FDG-PET with glucose loading and thallium-201 (201Tl) reinjection imaging. Expand
Relation between the kinetics of thallium-201 in myocardial scintigraphy and myocardial metabolism in patients with acute myocardial infarction
Thallium-201Myocardial scintigraphy provides information about not only myocardial perfusion and viability but also about myocardials metabolism in patients with acute myocardIAL infarction. Expand
Thallium-201 for Detection of Myocardial Viability: Comparison of Early Postexercise Reinjection and Imaging with 4 and 18–24 Hours Redistribution Imaging
By eliminating the need for an additional delayed set of images for detection of myocardial viability, this protocol reduces the total investigation procedure, is more convenient for the patient, increases patient turnover and expedites the decision-making process. Expand
Comparison of thallium-201 single-photon emission tomography after rest injection and fluorodeoxyglucose positron emission tomography for assessment of myocardial viability in patients with chronic coronary artery disease
It is concluded that 201Tl SPET using a rest protocol identifies viable myocardium in the supply area of the LAD and in the lateral wall with high accuracy compared to 18FDG positron emission tomography while disordance in the posterior territory may be governed by photon attenuation in the SPET study rather than by a pathophysiological difference. Expand
Usefulness of reinjection image for evaluating viable myocardium in the infarcted zone on exercise thallium-201 SPECT
It has been demonstrated that underestimated viable myocardium on 4 hour delayed images in the infarcted zone can be better assessed on reinjection images and this reinjection technique is recommended in patients with no or partial redistribution on 4 hours delayed images. Expand
Assessment of myocardial viability in patients with previous myocardial infarction by using single-photon emission computed tomography with a new metabolic tracer: [123I]-16-iodo-3-methylhexadecanoic acid (MIHA). Comparison with the rest-reinjection thallium-201 technique.
MIHA is an efficient marker of viability inside exercise-underperfused areas after infarction, even in patients with irreversible Tl-201 reinjection defects, and is assessed by conventional SPECT of a mismatch between results obtained with a metabolic tracer and a flow tracer analyzed at exercise as a marker of myocardial viability. Expand
Assessment of myocardial perfusion and viability with technetium-99m methoxyisobutylisonitrile and thallium-201 rest redistribution in chronic coronary artery disease
There is an inverse relationship between the severity of99mTc-MIBI perfusion defects and the uptake of rest-redistributed201Tl and [18F]FDG and both tracers are adequate markers of viability in mild and moderate defects. Expand
Metabolic myocardial viability assessment with iodine 123-16-iodo-3-methylhexadecanoic acid in recent myocardial infarction: Comparison with thallium-201 and fluorine-18 fluorodeoxyglucose
In patients with recent myocardial infarction, MIHA accurately detects the persistence of metabolic viability, but is not superior to T1, and its contribution compared with the stress-redistribution-reinjection technique is evaluated. Expand


Relation of left ventricular perfusion and wall motion with metabolic activity in persistent defects on thallium-201 tomography in healed myocardial infarction.
To assess metabolic activity in segments with persistent defect, stress TI-201 tomography and positron emission tomography using nitrogen-13 ammonia and fluorine-18 2-fluoro-deoxyglucose (FDG) were performed in 28 patients with healed myocardial infarction and data indicate that metabolic viability was observed in approximately 40% of the segments. Expand