Metabolic actions of natriuretic peptides and therapeutic potential in the metabolic syndrome.

@article{Schlueter2014MetabolicAO,
  title={Metabolic actions of natriuretic peptides and therapeutic potential in the metabolic syndrome.},
  author={Nina Schlueter and Anita de Sterke and Diana M. Willmes and Joachim Spranger and Jens Jordan and Andreas L Birkenfeld},
  journal={Pharmacology & therapeutics},
  year={2014},
  volume={144 1},
  pages={12-27}
}
Natriuretic peptides (NPs) are a group of peptide-hormones mainly secreted from the heart, signaling via c-GMP coupled receptors. NP are well known for their renal and cardiovascular actions, reducing arterial blood pressure as well as sodium reabsorption. Novel physiological functions have been discovered in recent years, including activation of lipolysis, lipid oxidation, and mitochondrial respiration. Together, these responses promote white adipose tissue browning, increase muscular… CONTINUE READING

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