Metabolic acidosis and the importance of balanced equations

@article{Lane2008MetabolicAA,
  title={Metabolic acidosis and the importance of balanced equations},
  author={A. Lane and T. Fan and R. Higashi},
  journal={Metabolomics},
  year={2008},
  volume={5},
  pages={163-165}
}
Balancing biochemical equations for both mass and charge in metabolic networks is critical but unfortunately ignored too often. Failure to do so, for example, results in a common misconception about the origin of protons during lactic fermentation. Lactate, rather than lactic acid, is produced by glycolysis, and its production is a mechanism for alleviating intracellular acidosis due to glycolysis. This error is at the core of some recent papers, and is often ambiguous in biochemistry textbooks… Expand
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