Metabolic abnormalities in cachexia and anorexia.

  title={Metabolic abnormalities in cachexia and anorexia.},
  author={Michael John Tisdale},
  volume={16 10},
An increased glucose requirement by many solid tumors produces an increased metabolic demand on the liver, resulting in an increased energy expenditure. In addition, several cytokines and tumor catabolic products have been suggested as being responsible for the depletion of adipose tissue and skeletal-muscle mass in cachexia. A sulphated glycoprotein of molecular mass 24 kDa, produced by cachexia-inducing tumors and present in the urine of cancer patients actively losing weight, has been shown… CONTINUE READING


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