Metabolic abnormalities and oxidative stress in lupus.

@article{Lightfoot2017MetabolicAA,
  title={Metabolic abnormalities and oxidative stress in lupus.},
  author={Yaima Luzardo Lightfoot and Luz Helena Pati{\~n}o Blanco and Mariana J Kaplan},
  journal={Current opinion in rheumatology},
  year={2017},
  volume={29 5},
  pages={
          442-449
        }
}
PURPOSE OF REVIEW Upon antigen exposure, immune cells rely on cell-specific metabolic pathways to mount an efficient immune response. In autoimmunity, failure in critical metabolic checkpoints may lead to immune cell hyperactivation and tissue damage. Oxidative stress in autoimmune patients can also contribute to immune dysregulation and injury to the host. Recent insights into the immune cell metabolism signatures, specifically associated with systemic lupus erythematosus (SLE) and the… CONTINUE READING
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