Metabolic Signatures of Cultured Human Adipocytes from Metabolically Healthy versus Unhealthy Obese Individuals

@inproceedings{Bhm2014MetabolicSO,
  title={Metabolic Signatures of Cultured Human Adipocytes from Metabolically Healthy versus Unhealthy Obese Individuals},
  author={Anja B{\"o}hm and Anna Halama and Tobias Meile and Marty Zdichavsky and Rainer Lehmann and Cora Weigert and Andreas Fritsche and Norbert Stefan and Alfred Koenigsrainer and Hans-Ulrich H{\"a}ring and Martin Hrabe de Angelis and Jerzy Adamski and Harald Staiger},
  booktitle={PloS one},
  year={2014}
}
BACKGROUND AND AIMS Among obese subjects, metabolically healthy and unhealthy obesity (MHO/MUHO) can be differentiated: the latter is characterized by whole-body insulin resistance, hepatic steatosis, and subclinical inflammation. Aim of this study was, to identify adipocyte-specific metabolic signatures and functional biomarkers for MHO versus MUHO. METHODS 10 insulin-resistant (IR) vs. 10 insulin-sensitive (IS) non-diabetic morbidly obese (BMI >40 kg/m2) Caucasians were matched for gender… CONTINUE READING

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