Metabolic Reprogramming and the Recovery of Physiological Functionality in 3D Cultures in Micro-Bioreactors †

@inproceedings{Wrzesinski2018MetabolicRA,
  title={Metabolic Reprogramming and the Recovery of Physiological Functionality in 3D Cultures in Micro-Bioreactors †},
  author={Krzysztof Wrzesinski and Stephen John Fey},
  booktitle={Bioengineering},
  year={2018}
}
The recovery of physiological functionality, which is commonly seen in tissue mimetic three-dimensional (3D) cellular aggregates (organoids, spheroids, acini, etc.), has been observed in cells of many origins (primary tissues, embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), and immortal cell lines). This plurality and plasticity suggest that probably several basic principles promote this recovery process. The aim of this study was to identify these basic principles and… CONTINUE READING
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References

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Endoplasmic reticulum and the unfolded protein response: dynamics and metabolic integration.

International review of cell and molecular biology • 2013
View 4 Excerpts
Highly Influenced

Asymmetric arginine dimethylation of RelA provides a repressive mark to modulate TNFα/NF-κB response.

Proceedings of the National Academy of Sciences of the United States of America • 2016
View 14 Excerpts
Highly Influenced

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity.

Proceedings of the National Academy of Sciences of the United States of America • 2010
View 4 Excerpts
Highly Influenced

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