Metabolic Reprogramming Supports IFN-γ Production by CD56bright NK Cells.

Abstract

Human NK cells can be classified into phenotypically and functionally distinct subsets based on levels of CD56 receptor. CD56(dim) cells are generally considered more cytotoxic, whereas the CD56(bright) cells are potent producers of IFN-γ. In this study, we define the metabolic changes that occur in peripheral blood NK cells in response to cytokine… (More)
DOI: 10.4049/jimmunol.1501783

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