Metabolic Profiles of Propofol and Fospropofol: Clinical and Forensic Interpretative Aspects

@inproceedings{DinisOliveira2018MetabolicPO,
  title={Metabolic Profiles of Propofol and Fospropofol: Clinical and Forensic Interpretative Aspects},
  author={Ricardo Jorge Dinis-Oliveira},
  booktitle={BioMed research international},
  year={2018}
}
Propofol is an intravenous short-acting anesthetic widely used to induce and maintain general anesthesia and to provide procedural sedation. The potential for propofol dependency and abuse has been recognized, and several cases of accidental overdose and suicide have emerged, mostly among the health professionals. Different studies have demonstrated an unpredictable interindividual variability of propofol pharmacokinetics and pharmacodynamics with forensic and clinical adverse relevant outcomes… CONTINUE READING
4
Twitter Mentions

References

Publications referenced by this paper.
SHOWING 1-10 OF 184 REFERENCES

Death from propofol: accident, suicide, or murder?

  • Anesthesia and analgesia
  • 2009
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Tissue mRNA expression of the rat UDP-glucuronosyltransferase gene family.

  • Drug metabolism and disposition: the biological fate of chemicals
  • 2003
VIEW 13 EXCERPTS
HIGHLY INFLUENTIAL

Disposition in male volunteers of a subanaesthetic intravenous dose of an oil in water emulsion of 14C-propofol.

  • Xenobiotica; the fate of foreign compounds in biological systems
  • 1988
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Death by Propofol.

  • The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society
  • 2017
VIEW 1 EXCERPT