Metabolic Phenotypes in Pancreatic Cancer

  title={Metabolic Phenotypes in Pancreatic Cancer},
  author={Min Yu and Quanbo Zhou and Yu Zhou and Zhiqiang Fu and Langping Tan and Xiao Juan Ye and Bing Zeng and Wenchao Gao and Jiajia Zhou and Yiming Liu and Zhihua Li and Ye Lin and Qing Lin and Rufu Chen},
  booktitle={PloS one},
INTRODUCTION The aim of present study was to profile the glucose-dependent and glutamine- dependent metabolism in pancreatic cancer. METHODS We performed Immunohistochemical staining of GLUT1, CAIX, BNIP3, p62, LC3, GLUD1, and GOT1. Based on the expression of metabolism-related proteins, the metabolic phenotypes of tumors were classified into two categories, including glucose- and glutamine-dependent metabolism. There were Warburg type, reverse Warburg type, mixed type, and null type in… CONTINUE READING
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