Metabolic Peculiarities of Paracoccidioides brasiliensis Dimorphism as Demonstrated by iTRAQ Labeling Proteomics

@inproceedings{Arajo2019MetabolicPO,
  title={Metabolic Peculiarities of Paracoccidioides brasiliensis Dimorphism as Demonstrated by iTRAQ Labeling Proteomics},
  author={Danielle Silva Ara{\'u}jo and Maristela Pereira and Igor Godinho Portis and A C M Dos Santos J{\'u}nior and Wagner Fontes and Marcelo Valle de Sousa and Leandro do Prado Assunç{\~a}o and L{\'i}lian Cristiane Baeza and Alexandre Mello Bail{\~a}o and Carlos Andr{\'e} Ornelas Ricart and Matthias Brock and C{\'e}lia Maria de Almeida Soares},
  booktitle={Front. Microbiol.},
  year={2019}
}
Paracoccidioidomycosis (PCM), a systemic mycosis with a high incidence in Latin America, is caused by thermodimorphic fungi of the Paracoccidioides genus. The contact with host occurs by the inhalation of conidia or mycelial propagules which once reaching the pulmonary alveoli differentiate into yeast cells. This transition process is vital in the pathogenesis of PCM allowing the fungus survival in the host. Thus, the present work performed a comparative proteome analysis of mycelia, mycelia-to… CONTINUE READING

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