Metabolic Patterns and Biotransformation Activities of Resveratrol in Human Glioblastoma Cells: Relevance with Therapeutic Efficacies

@inproceedings{Shu2011MetabolicPA,
  title={Metabolic Patterns and Biotransformation Activities of Resveratrol in Human Glioblastoma Cells: Relevance with Therapeutic Efficacies},
  author={Xiao-hong Shu and Hong Li and X. L. Sun and Qian Wang and Zheng Sun and Mo-li Wu and Xiaoyan Chen and Chong Li and Qing-you Kong and Jia Liu},
  booktitle={PloS one},
  year={2011}
}
BACKGROUND Trans-resveratrol rather than its biotransformed monosulfate metabolite exerts anti-medulloblastoma effects by suppressing STAT3 activation. Nevertheless, its effects on human glioblastoma cells are variable due to certain unknown reason(s). METHODOLOGY/PRINCIPAL FINDINGS Citing resveratrol-sensitive UW228-3 medulloblastoma cell line and primarily cultured rat brain cells/PBCs as controls, the effect of resveratrol on LN-18 human glioblastoma cells and its relevance with metabolic… CONTINUE READING
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