Metabolic PathFinding: inferring relevant pathways in biochemical networks

Abstract

Our knowledge of metabolism can be represented as a network comprising several thousands of nodes (compounds and reactions). Several groups applied graph theory to analyse the topological properties of this network and to infer metabolic pathways by path finding. This is, however, not straightforward, with a major problem caused by traversing irrelevant… (More)
DOI: 10.1093/nar/gki437

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