Metabolic Network 10-24-2017 Role of Granulocyte-Macrophage Colony-Stimulating Factor Production by T Cells during Mycobacterium tuberculosis Infection

@inproceedings{Rothchild2018MetabolicN1,
  title={Metabolic Network 10-24-2017 Role of Granulocyte-Macrophage Colony-Stimulating Factor Production by T Cells during Mycobacterium tuberculosis Infection},
  author={Alissa C. Rothchild and Britni L. Stowell and Girija Goyal and Cl{\'a}udio Nunes-Alves and Qianting Yang and Kadamba Papavinasasundaram and Christopher M. Sassetti and Glenn Dranoff and Xinchun Chen and Jinhee Lee and Samuel M. Beharb},
  year={2018}
}
Mice deficient for granulocyte-macrophage colony-stimulating factor (GM-CSF / ) are highly susceptible to infection with Mycobacterium tuberculosis, and clinical data have shown that anti-GM-CSF neutralizing antibodies can lead to increased susceptibility to tuberculosis in otherwise healthy people. GM-CSF activates human and murine macrophages to inhibit intracellular M. tuberculosis growth. We have previously shown that GM-CSF produced by iNKT cells inhibits growth of M. tuberculosis. However… CONTINUE READING
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T cell-derived GM-CSF, regulation of expression and function

  • W. Sheng
  • Immunome Res
  • 2015
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