Metabolic Mapping of the Effects of Win 55212–2 Intravenous Administration in the Rat

Abstract

The [14C]2-deoxyglucose method was applied to measure the effects of the synthetic cannabinoid agonist WIN 55212-2 intravenous administration on glucose utilization in the rat brain. Two doses of the drug, that have been reported previously to increase extracellular dopamine concentrations in the shell of the nucleus accumbens, were used (0.15–0.30 mg/kg… (More)
DOI: 10.1016/S0893-133X(99)00064-0

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