Metabolic Fuel Privation in Hibernating and Awake Ground Squirrels

  title={Metabolic Fuel Privation in Hibernating and Awake Ground Squirrels},
  author={John Dark and Dawn R. Miller},
  journal={Physiology & Behavior},
The nature of metabolic fuel utilization during hibernation and periodic arousal is not completely understood. 2-Deoxy-D-glucose (2DG) and mercaptoacetate (MA) were administered to hibernating ground squirrels. These drugs disrupt glucose and fatty acid oxidation, respectively. Telemetrically recorded body temperature (Tb) was analyzed to determine rate of rewarming from hibernation, duration of euthermia during periodic arousal, and proportion of animals arousing after treatments. 2DG given… CONTINUE READING


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