Metabolic Engineering of the Shikimate Pathway for Production of Aromatics and Derived Compounds—Present and Future Strain Construction Strategies

@inproceedings{Averesch2018MetabolicEO,
  title={Metabolic Engineering of the Shikimate Pathway for Production of Aromatics and Derived Compounds—Present and Future Strain Construction Strategies},
  author={Nils J H Averesch and Jens O. Kr{\"o}mer},
  booktitle={Front. Bioeng. Biotechnol.},
  year={2018}
}
The aromatic nature of shikimate pathway intermediates gives rise to a wealth of potential bio-replacements for commonly fossil fuel-derived aromatics, as well as naturally produced secondary metabolites. Through metabolic engineering, the abundance of certain intermediates may be increased, while draining flux from other branches off the pathway. Often… CONTINUE READING