Metabolic Compartmentation – A System Level Property of Muscle Cells

@article{Saks2008MetabolicC,
  title={Metabolic Compartmentation – A System Level Property of Muscle Cells},
  author={V. Saks and Nathalie B{\'e}raud and Theo Wallimann},
  journal={International Journal of Molecular Sciences},
  year={2008},
  volume={9},
  pages={751 - 767}
}
Problems of quantitative investigation of intracellular diffusion and compartmentation of metabolites are analyzed. Principal controversies in recently published analyses of these problems for the living cells are discussed. It is shown that the formal theoretical analysis of diffusion of metabolites based on Fick's equation and using fixed diffusion coefficients for diluted homogenous aqueous solutions, but applied for biological systems in vivo without any comparison with experimental results… CONTINUE READING

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Integrated and Organized Cellular Energetic Systems: Theories of Cell Energetics, Compartmentation and Metabolic Channeling

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Mechanisms and Modeling of Energy Transfer Between and Among Intracellular Compartments

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The Phosphocreatine Circuit: Molecular and Cellular Physiology of Creatine Kinases, Sensitivity to Free Radicals, and Enhancement by Creatine Supplementation

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