Metabolic, autophagic, and mitophagic activities in cancer initiation and progression

@inproceedings{Hjelmeland2016MetabolicAA,
  title={Metabolic, autophagic, and mitophagic activities in cancer initiation and progression},
  author={Anita B. Hjelmeland and Jianhua Zhang},
  booktitle={Biomedical journal},
  year={2016}
}
Cancer is a complex disease marked by uncontrolled cell growth and invasion. These processes are driven by the accumulation of genetic and epigenetic alterations that promote cancer initiation and progression. Contributing to genome changes are the regulation of oxidative stress and reactive species-induced damage to molecules and organelles. Redox regulation, metabolic plasticity, autophagy, and mitophagy play important and interactive roles in cancer hallmarks including sustained… CONTINUE READING
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The dual role of ROS, antioxidants and autophagy in cancer

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