Metaanalysis of prophylactic drug treatment in the prevention of postoperative bleeding.

@article{Fremes1994MetaanalysisOP,
  title={Metaanalysis of prophylactic drug treatment in the prevention of postoperative bleeding.},
  author={Stephen E. Fremes and Bill Wong and Eileen Lee and R Mai and George T Christakis and R F Mclean and Bernard S. Goldman and C. David Naylor},
  journal={The Annals of thoracic surgery},
  year={1994},
  volume={58 6},
  pages={1580-8}
}
Prophylactic drug treatment is one of several strategies to reduce postoperative blood loss and potentially limit homologous blood use in open heart surgery. A computerized MEDLINE search supplemented with manual bibliography reviews was performed for randomized clinical trials published in peer-reviewed English-language journals from January 1980 to June 1993. A metaanalysis was conducted of trials evaluating desmopressin (group DD, n = 13), epsilon-aminocaproic acid or tranexamic acid (group… CONTINUE READING

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