Meta-analytic evaluation of the association between head injury and risk of amyotrophic lateral sclerosis

  title={Meta-analytic evaluation of the association between head injury and risk of amyotrophic lateral sclerosis},
  author={Y. Watanabe and T. Watanabe},
  journal={European Journal of Epidemiology},
  • Y. Watanabe, T. Watanabe
  • Published 2017
  • Medicine
  • European Journal of Epidemiology
  • Head injury is considered as a potential risk factor for amyotrophic lateral sclerosis (ALS). However, several recent studies have suggested that head injury is not a cause, but a consequence of latent ALS. We aimed to evaluate such a possibility of reverse causation with meta-analyses considering time lags between the incidence of head injuries and the occurrence of ALS. We searched Medline and Web of Science for case–control, cross-sectional, or cohort studies that quantitatively investigated… CONTINUE READING
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