Meta-analysis on the G-308A tumor necrosis factor alpha gene variant and phenotypes associated with the metabolic syndrome.

@article{Sookoian2005MetaanalysisOT,
  title={Meta-analysis on the G-308A tumor necrosis factor alpha gene variant and phenotypes associated with the metabolic syndrome.},
  author={Silvia Sookoian and Claudio Daniel Gonz{\'a}lez and Carlos J Pirola},
  journal={Obesity research},
  year={2005},
  volume={13 12},
  pages={2122-31}
}
OBJECTIVE The G-308A tumor necrosis factor (TNF) alpha gene variant has been associated with obesity, insulin resistance, and hypertension. We performed a systematical review of the literature by means of a meta-analysis to assess the association of the G-308A TNFalpha polymorphism with the components of the metabolic syndrome. RESEARCH METHODS AND PROCEDURES Studies were identified by searches of the literature for reports using the terms: diabetes, insulin resistance, hypertension, obesity… CONTINUE READING

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