Meta-analysis of the heritability of human traits based on fifty years of twin studies
@article{Polderman2015MetaanalysisOT, title={Meta-analysis of the heritability of human traits based on fifty years of twin studies}, author={Tinca J. C. Polderman and Beben Benyamin and Christiaan A. de Leeuw and Patrick F. Sullivan and Arjen van Bochoven and Peter M. Visscher and Danielle Posthuma}, journal={Nature Genetics}, year={2015}, volume={47}, pages={702-709} }
Despite a century of research on complex traits in humans, the relative importance and specific nature of the influences of genes and environment on human traits remain controversial. [] Key Method We report a meta-analysis of twin correlations and reported variance components for 17,804 traits from 2,748 publications including 14,558,903 partly dependent twin pairs, virtually all published twin studies of complex traits. Estimates of heritability cluster strongly within functional domains, and across all…
1,558 Citations
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