Meta-analysis of the effects of eicosapentaenoic acid (EPA) in clinical trials in depression.

@article{Sublette2011MetaanalysisOT,
  title={Meta-analysis of the effects of eicosapentaenoic acid (EPA) in clinical trials in depression.},
  author={Mary Elizabeth Sublette and Steven P. Ellis and Amy L. Geant and J J Mann},
  journal={The Journal of clinical psychiatry},
  year={2011},
  volume={72 12},
  pages={
          1577-84
        }
}
OBJECTIVE Randomized trials of omega-3 polyunsaturated fatty acid (PUFA) treatment for depression have differed in outcome. Recent meta-analyses ascribe discrepancies to differential effects of eicosapentaenoic acid (EPA) versus docosahexaenoic acid (DHA) and to diagnostic heterogeneity. This meta-analysis tests the hypothesis that EPA is the effective component in PUFA treatment of major depressive episodes. DATA SOURCES PubMed/MeSH was searched for studies published in English from 1960… CONTINUE READING

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