Meta-analysis of the cognitive effects of the catechol-O-methyltransferase gene Val158/108Met polymorphism.

@article{Barnett2008MetaanalysisOT,
  title={Meta-analysis of the cognitive effects of the catechol-O-methyltransferase gene Val158/108Met polymorphism.},
  author={Jennifer H. Barnett and Linda Scoriels and Marcus R Munaf{\`o}},
  journal={Biological psychiatry},
  year={2008},
  volume={64 2},
  pages={137-44}
}
BACKGROUND Cognitive endophenotypes may further our understanding of the genetic basis of psychiatric disorders, and the catechol-O-methyltransferase (COMT) gene is a promising candidate gene for both cognitive function and disorder. We conducted a meta-analysis of reported associations between the COMT Val158/108Met polymorphism and measures of memory and executive function. METHODS The PubMed database was searched for studies relating cognitive functions and the COMT Val158/108Met… CONTINUE READING
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