Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls.

@article{Casas2004MetaanalysisOG,
  title={Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls.},
  author={Juan P. Casas and Aroon D. Hingorani and Leonelo Enrique Bautista and Pankaj Sharma},
  journal={Archives of neurology},
  year={2004},
  volume={61 11},
  pages={1652-61}
}
Ischemic stroke is thought to have a polygenic basis, but identification of stroke susceptibility genes and quantification of associated risks have been hampered by conflicting results from underpowered case-control studies. We performed a meta-analysis of all candidate gene association studies in ischemic stroke. Electronic databases were searched up until January 2003 for all case-control and nested case-control studies in English-language journals relating to the investigation of any… CONTINUE READING

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